Glycosyl compounds
Cayman Chemical n-DodecylD-maltosIde 500mg
A non-ionic detergent commonly used to solubilize membrane-associated proteins; helps retain the native conformation and activity of membrane-associated proteins, and facilitates the reforming of these proteins after denaturation
Apexbio Technology LLC ISRIB (trans-isomer) 1597403-47-8 10mM (in 1mL DMSO)
ISRIB (trans-isomer) (CAS 1597403-47-8) is a small molecule inhibitor of the integrated stress response (ISR) ISR activation involves the phosphorylation of eukaryotic initiation factor 2 (eIF2 ) by stress-sensitive kinases leading to reduced global protein synthesis and enhanced translation of select mRNAs ISRIB counteracts ISR signaling by reversing the translational suppression induced by phosphorylated eIF2 inhibiting production of ATF4 protein decreasing stress granule assembly and promoting polyribosome formation during endoplasmic reticulum (ER) stress ISRIB stabilizes and activates eIF2B by facilitating its dimerization Rodent studies demonstrate ISRIB s capacity to enhance hippocampal-dependent spatial and fear-related learning and memory highlighting its utility in neuroscience research
Medchemexpress LLC Alpha,beta-trehalose | 585-91-1 | MFCD00006628 | 99.7% | 342.30 g·mol⁻¹ | C12H22O11 | 1 MG
α,β-Trehalose is a disaccharide biochemical reagent supplied as a white to off-white solid for life-science research and biochemical assays. It is used as a stabilizer and experimental carbohydrate standard in laboratory workflows, and is provided with supporting documentation for safe handling and characterization.
- High chemical purity suitable for analytical applications.
- Supplied as a small-quantity solid for research use.
- Stable solid with defined cold storage recommendations.
- Provided with SDS, COA, and datasheet for quality and safety verification.
- Water soluble for preparing assay and buffer solutions.
Medchemexpress LLC N-oleoylethanolamide-d4 | 946524-36-3 | 99.0% | 329.55 | C20H35D4NO2 | 1 MG
Oleoylethanolamide-d4 is the deuterium-labeled analog of oleoylethanolamide used as a stable isotope reference standard and tracer in biochemical and metabolic research. Supplied in small, high-purity solution quantities, it supports analytical quantification, tracer studies, and method development.
- High purity suitable for analytical use.
- Deuterium-labeled internal standard for tracer and quantitation studies.
- Molecular weight 329.55 and formula C20H35D4NO2.
- Supplied as a solution for ease of handling and accurate dosing.
- Recommended storage at -20°C for up to two years.
Medchemexpress LLC Pulsatilla saponin D | 68027-15-6 | 913.10 | 1 ML
Pulsatilla saponin D (SB365), also known as Hederacolchiside A, is a natural product isolated from the root of Pulsatilla chinensis. It is an anti-tumor agent.
- Shows apoptotic effect.
- Strongly inhibits c-Met expression in gastric cancer cells.
- Suppresses the growth and proliferation of 5 human pancreatic cancer cell lines.
- Exhibits anti-angiogenic activity.
- Shows anti-tumor activity in NSCLC cancer cells.
- Demonstrates anti-tumor activity in a Lewis lung carcinoma model.
Medchemexpress LLC 2-O-α-D-Glucopyranosyl-L-ascorbic Acid | 129499-78-1 | 100 MG
2-O-α-D-Glucopyranosyl-L-ascorbic Acid is an orally active glucoside derivative of ascorbic acid that can be hydrolyzed by α-glucosidase to release ascorbic acid. It is used in research related to tumors, inflammation, and other conditions.
- Inhibits melanin synthesis
- Prevents UV-induced cell damage
- Promotes collagen synthesis in skin fibroblasts
- Induces oxidative stress to inhibit tumor growth
![Medchemexpress LLC N,N'-trans-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)acetamide] | 1597403-47-8 | MFCD27952932 | 99.5% | 451.34 g/mol | C22H24Cl2N2O4 | 10MM 1ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000235622.png-250.jpg)
Medchemexpress LLC N,N'-trans-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)acetamide] | 1597403-47-8 | MFCD27952932 | 99.5% | 451.34 g/mol | C22H24Cl2N2O4 | 10MM 1ML
ISRIB (trans-isomer) is a small-molecule inhibitor of the integrated stress response that potently inhibits PERK and reverses eIF2α phosphorylation. It is supplied as a 10 mM solution in DMSO or as solid quantities for use in biochemical and cellular assays; reported purity is 99.49% and molecular weight 451.34 g/mol.
- Potent PERK inhibition with reported IC50 of 5 nM.
- Reverses eIF2α phosphorylation in cellular assays.
- Available as 10 mM solution in DMSO and multiple solid sizes.
- High purity suitable for research applications.
- Molecular weight 451.34 g/mol and formula C22H24Cl2N2O4.
- Useful for biochemical and cell-based studies of the integrated stress response.
Medchemexpress LLC D-Tetrahydropalmatine | 3520-14-7 | MFCD11046348 | 355.43 | 1 ML
D-Tetrahydropalmatine is an isoquinoline alkaloid primarily found in the genus Corydalis. It acts as a dopamine (DA) receptor antagonist, showing preferential affinity for D1 receptors. Additionally, it is identified as a potent inhibitor of organic cation transporter 1 (OCT1).
- Dopamine receptor antagonist
- Preferential affinity toward the D1 receptors
- Potent organic cation transporter 1 (OCT1) inhibitor
- Purity: 99.84%
- Appearance: Solid
- Color: White to light yellow
- Initial source: Plants Papaveraceae Corydalis yanhusuo W. T. Wang
Medchemexpress LLC D-N-Acetylgalactosamine | 1811-31-0 | MFCD00135832 | 97.0% | 221.21 | 1 ML
D-N-Acetylgalactosamine is an endogenous metabolite. It is a cell surface glycosylation residue that participates in cell-cell/cell-matrix interaction as a recognition site for cell surface receptors. It binds to the asialoglycoprotein receptor (ASGPR) on hepatocytes via the terminal glycosylated protein, affecting the interaction between apoptotic extracellular vesicles (apoEVs) and ASGPR, blocking the internalization of apoEVs, and thereby blocking the regulatory effect of apoEVs on the liver, affecting liver homeostasis and regeneration.
- Endogenous metabolite
- Cell surface glycosylation residue
- Participates in cell-cell/cell-matrix interaction as a recognition site for cell surface receptors
- Binds to asialoglycoprotein receptor (ASGPR) on hepatocytes
Medchemexpress LLC Complement Factor D/ 50ug | 50ug
Complement Factor D/Adipsin Protein cleaves factor B in complex with factor C3b activating the C3bbb complex to form the C3 convertase in the alternate pathway analogous to C1s in the classical pathway Complement Factor D/Adipsin Protein Mouse (HEK293 Fc) is the recombinant mouse-derived Complement Factor D/Adipsin protein expressed by HEK293 with C-hFc labeled tag
Medchemexpress LLC Sucrose (standard) | 57-50-1 | 99.8% | 50 MG
Sucrose (Standard) is the analytical standard of Sucrose, intended for research and analytical applications. It is a disaccharide composed of two monosaccharides, glucose and fructose. Sucrose can be applied in animal models for metabolic disease, obesity, diet on preference, and diabetes. This compound is an analytical standard, used as a reference standard in assays, and is commonly applied in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Analytical standard for sucrose.
- Composed of glucose and fructose.
- Applicable in animal models for metabolic disease, obesity, diet on preference, and diabetes.
- Used in qualitative, quantitative, and methodological research experiments including hplc, gc, and ms.
- Appearance: solid, white to off-white.
Medchemexpress LLC Tau-D/0N4R Human 1 500ug
Recombinant human Tau-D/0N4R is a 133-amino-acid fragment of microtubule-associated protein tau supplied with a C-terminal 6xHis tag. Expressed in E. coli and provided lyophilized from PBS with 1 mM PMSF, the product is >95% pure by reducing SDS-PAGE and is suitable for biochemical, biophysical, and assay development studies related to tau function and aggregation.
- Contains 133 amino acids with a C-terminal 6xHis tag.
- Expressed in E. coli for consistent recombinant production.
- Greater than 95% purity as determined by reducing SDS-PAGE.
- Lyophilized from PBS with 1 mM PMSF for stability.
- Stable refrigerated short term or frozen for long-term storage.
- Not recommended to reconstitute below 100 μg/mL in ddH2O.
Medchemexpress LLC Schisantherin D | 64917-82-4 | 5 MG
Schisantherin D is a dibenzocyclooctadiene lignan isolated from the fruit of *Schisandra sphenanthera*. It demonstrates anti-HIV replication activities with an EC50 of 0.5 μg/mL. Additionally, Schisantherin D inhibits endothelin receptor B (ETBR) and exhibits hepatoprotective effects.
- Dibenzocyclooctadiene lignan
- Isolated from the fruit of *Schisandra sphenanthera*
- Demonstrates anti-HIV replication activities
- Inhibits endothelin receptor B (ETBR)
- Exhibits hepatoprotective effects